Involved in early development of embryos, especially in the process of gastrulation.
May play an important role in establishing and specifying rhombomeric segments.
Seems to be required to maintain the cells in a highly undifferentiated state.
In contrast to POU2, T-POU2 lacks DNA-binding activity because of its incomplete pou domain structure.
Overexpression of POU2 does not have any effect on development, whereas overexpression of t- POU2 causes developmental retardation or arrest before gastrulation.
Applications:Suitable for use in ELISA, Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：Zebrafish
Grade：Affinity Purified
Purity：Purified by Protein A and peptide affinity chromatography.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes zebrafish DANRE pou5f1.
Isotype：IgG
Calc Applications Abbrev：E WB
Calc Crossreactivity：Ze
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within aa128-161 of the N-terminal region of zebrafish DANRE pou5f1.
