Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction.
Undergoes a functional cycle that is linked to its ATPase activity.
This cycle probably induces conformational changes in the client proteins, thereby causing their activation.
Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
Applications:Suitable for use in ELISA, Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A and peptide affinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes human HSP90. Species Crossreactivity: mouse, rat.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu Mo Rt
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within aa57-89 of the N-terminal region of human HSP90. Species sequence homology: zebrafish, bovine, chicken, hamster, equine, monkey, porcine, rabbit, drosophila.