84-5116-08 H2AFY2, ID 200ul 501771
特徴
- Variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription.
- Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template.
- Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability.
- DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
- May be involved in stable X chromosome inactivation.
- Applications:Suitable for use in ELISA, Western Blot.
- Other applications not tested.
- Recommended Dilution:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size:200ul
- Host:rabbit
- Source Antibody:human
- Grade:Affinity Purified
- Purity:Purified by Protein A and peptide affinity chromatography.
- Form:Supplied as a liquid in PBS, 0.09% sodium azide.
- Specificity:Recognizes human H2AFY2.
- Isotype:IgG
- Calc Applications Abbrev:E WB
- Calc Crossreactivity:Hu
- Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within aa148-169 of the Central region of human H2AFY2.
- Shelf Life:1year
- Swiss Prot Number:Q9P0M6
- EU Commodity Code:30021010
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