Netrins control guidance of CNS commissural axons and peripheral motor axons.
Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively.
It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis.
Involved in tumorigenesis by regulating apoptosis.
Applications:Suitable for use in ELISA, Western Blot.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:200ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by Protein A and peptide affinity chromatography.
Form:Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity:Recognizes zebrafish NTN1.
Isotype:IgG
Calc Applications Abbrev:E WB
Calc Crossreactivity:Hu
Immunogen:KLH-conjugated synthetic peptide mapping to a fragment of residues within aa568-596 of the C-terminal region of human NTN1. Species sequence homology: chicken, mouse, porcine.