Dual-specificity phosphatases, a subfamily of protein-tyrosine phosphatases, play important roles in signal transduction, cell cycle progression, and tumor suppression.
The cDNA encoding a novel phosphatase, PIR1, phosphatase that interacts with RNA/RNP complex 1.
Sequence analysis revealed that the predicted 329aa protein has homology to several dual-specificity phosphatases and contains 2 stretches of arginine-rich sequence similar to those found in some RNA-binding proteins.
In vitro, recombinant protein displays protein-tyrosine phosphatase activity and binds directly to RNA.
Applications:Suitable for use in ELISA, Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Western Blot: 1:1000Immunohistochemistry (Paraffin): 1:50-1:100Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：200ul
Host：rabbit
Source Antibody：human
Grade：Purified
Purity：Purified by ammonium sulfate precipitation.
Form：Supplied as a liquid in PBS, 0.09% sodium azide.
Specificity：Recognizes human DUSP13-L184.
Isotype：IgG
Calc Applications Abbrev：E IHC WB
Calc Crossreactivity：Hu
Immunogen：KLH-conjugated synthetic peptide mapping to a fragment of residues within aa169-198 of the C-terminal region of human DUSP13-L184.
