84-5101-40　YBX1 100ul　495743

特徴

• YBX1 binds to splice sites in pre-mRNA and regulates splice site selection.
• YBX1 binds and stabilizes cytoplasmic mRNA.
• YBX1 contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors.
• YBX1 binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as HLA class II genes.
• YBX1 regulates the transcription of numerous genes.
• YBX1 promotes separation of DNA strands that contain mismatches or are modified by cisplatin.
• YBX1 has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro).
• YBX1 may play a role in DNA repair.
• YBX1 is the component of the CRD-mediated complex that promotes MYC mRNA stability.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.