This gene encodes tumor protein p63, a member of the p53 family of transcription factors involved in cellular responses to stress and development.
The family members include tumor proteins p53, p63, and p73, which have high sequence similarity to one another.
This similarity allows p63 and p73 to transactivate p53-responsive genes causing cell cycle arrest and apoptosis.
The family members can interact with each other in many ways, including direct and indirect protein interactions.
This results in mutual regulation of target gene promoters.
Tumor protein p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
