84-5086-79　TOB1 (Protein Tob1, Transducer of ERBB2, 1) 100ul　494297

特徴

• This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth.
• When exogenously expressed, this protein supresses cell growth in tissue culture.
• The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase.
• Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression.
• This protein inhibits T cell proliferation and transcription of cytokines and cyclins.
• The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity.
• This interaction inhibits interleukin 2 transcription in T cells.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.