84-5086-29　TNFSF15 (Tumor Necrosis Factor Ligand Superfamily Member 15 100ul　494247

特徴

• The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family.
• This protein is abundantly expressed in endothelial cells, but is not expressed in either B or T cells.
• The expression of this protein is inducible by TNF and IL-1 alpha.
• This cytokine is a ligand for receptor TNFRSF25 and decoy receptor TNFRSF21/DR6.
• It can activate NF-kappaB and MAP kinases, and acts as an autocrine factor to induce apoptosis in endothelial cells.
• This cytokine is also found to inhibit endothelial cell proliferation, and thus may function as an angiogenesis inhibitor.
• Two transcript variants encoding different isoforms have been found for this gene.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.