Cancer-associated chromosomal changes often involve regions containing fragile sites.
This gene maps to a commom fragile site on chromosome 7q31.2 designated FRA7G.
This gene is similar to mouse Testin, a testosterone-responsive gene encoding a Sertoli cell secretory protein containing three LIM domains.
LIM domains are double zinc-finger motifs that mediate protein-protein interactions between transcription factors, cytoskeletal proteins and signaling proteins.
This protein is a negative regulator of cell growth and may act as a tumor suppressor.
This scaffold protein may also play a role in cell adhesion, cell spreading and in the reorganization of the actin cytoskeleton.
Multiple protein isoforms are encoded by transcript variants of this gene.
Applications:Suitable for use in Western Blot, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
