84-5079-88 TCHP (Trichoplein Keratin Filament-Binding Protein, Trichoplein, Keratin Filament Binding) 100ul 493613
特徴
- TCHP is a tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress.
- It inhibits cell growth in bladder and prostate cancer cells by a down-regulation of HSPB1 by inhibiting its phosphorylation.
- It may act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery.
- And it also may regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells.
- Applications:Suitable for use in Western Blot.
- Other applications not tested.
- Recommended Dilution:Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by affinity chromatography.
- Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
- Specificity：Recognizes human TCHP.
- Isotype：IgG
- Calc Applications Abbrev：WB
- Calc Crossreactivity：Hu
- Immunogen：Synthetic peptide corresponding to the C-terminal region of human TCHP
- Shelf Life：1year
- Swiss Prot Number：Q9BT92
- EU Commodity Code：30021010
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