Taf1c is a component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription.
The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter.
SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.
Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
Taf1c recruits RNA polymerase I to the rRNA gene promoter via interaction with RRN3.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity：Recognizes mouse TAF1C. Species Crossreactivity: guinea pig, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Gp Mo Rt
Immunogen：Synthetic peptide corresponding to a region of mouse TAF1C.
