84-5074-93　SUCLA2 (Succinyl-CoA Ligase [ADP-Forming] Subunit Beta, Mitochondrial, Succinate-CoA Ligase, ADP-Forming, Beta Subunit) 100ul　493123

特徴

• Succinyl-CoA synthetase (SCS) is a mitochondrial matrix enzyme that acts as a heterodimer, being composed of an invariant alpha subunit and a substrate-specific beta subunit.
• The protein encoded by this gene is an ATP-specific SCS beta subunit that dimerizes with the SCS alpha subunit to form SCS-A, an essential component of the tricarboxylic acid cycle.
• SCS-A hydrolyzes ATP to convert succinate to succinyl-CoA.
• Defects in this gene are a cause of myopathic mitochondrial DNA depletion syndrome.
• A pseudogene of this gene has been found on chromosome 6.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.