84-5073-65　STAT1 (Signal Transducer and Activator of Transcription 1-alpha/beta, Signal Transducer and Activator of Transcription 1, 91kD) 100ul　492996

特徴

• STAT1 is a member of the STAT protein family.
• In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.
• This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6.
• This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens.Western blots using four different antibodies against three unique regions of this protein target confirm the same apparent molecular weight in our tests.The protein encoded by this gene is a member of the STAT protein family.
• In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators.
• This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6.
• This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens.
• Two alternatively spliced transcript variants encoding distinct isoforms have been described.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.