84-5071-47　SPTLC2 (Serine Palmitoyltransferase 2, Serine Palmitoyltransferase, Long Chain Base Subunit 2) 100ul　492780

特徴

• SPTLC2 is a long chain base subunit of serine palmitoyltransferase.
• Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis.
• It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine.
• Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.This gene encodes a long chain base subunit of serine palmitoyltransferase.
• Serine palmitoyltransferase, which consists of two different subunits, is the key enzyme in sphingolipid biosynthesis.
• It catalyzes the pyridoxal-5-prime-phosphate-dependent condensation of L-serine and palmitoyl-CoA to 3-oxosphinganine.
• Mutations in this gene were identified in patients with hereditary sensory neuropathy type I.
• Alternatively spliced variants encoding different isoforms have been identified.
• PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-973 AB011098.1 1-973 974-1108 BQ338973.1 306-440 1109-3679 AB011098.1 1109-3679 3680-4578 AB011098.1 3682-4580 4579-4876 BG024616.1 326-623 4877-6812 AB011098.1 4879-6814 6813-7189 W24363.1 55-431 7190-7250 BM992457.1 1-61 c
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.