The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane.
SEC63 and SEC62 protein are found to be associated with ribosome-free SEC61 complex.
It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER.
The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway.
SEC63 is an integral membrane protein located in the rough ER.The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane.
The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex.
It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER.
The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway.
The encoded protein is an integral membrane protein located in the rough ER.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity：Recognizes human SEC63.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to the C-terminal region of human SEC63
