This gene encodes a DNA-binding protein which has high specificity for scaffold or matrix attachment region DNA elements(S/MAR DNA).
This protein is thought to be involved in attachingthe base of chromatin loops to the nuclear matrix but there isconflicting evidence as to whether this protein is a component of chromatin or a nuclear matrix protein.
Scaffold attachment factorsare a specific subset of nuclear matrix proteins (NMP) that specifically bind to S/MAR.
The encoded protein is thought to serveas a molecular base to assemble a 'transcriptosome complex' in thevicinity of actively transcribed genes.
It is involved in theregulation of heat shock protein 27 transcription, can act as anestrogen receptor co-repressor and is a candidate for breast tumorigenesis.
This gene is arranged head-to-head with a similar gene whose product has the same functions.
Multiple transcriptvariants encoding different isoforms have been found for this gene.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity：Recognizes human SAFB.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to the N-terminal region of human SAFB
