Rpsa is required for the assembly and/or stability of the 40S ribosomal subunit.
It is also required for the processing of the 20S rRNA-precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits.
It slso functions as a cell surface receptor for laminin.
It plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways.
It may play a role in cell fate determination and tissue morphogenesis.
It also acts as a receptor for several other ligands, including the pathogenic prion protein, viruses, and bacteria.
It enables malignant tumor cells to penetrate laminin tissue and vessel barriers and activates precursor thymic anti-OFA/iLRP specific cytotoxic T cell.
It may induce CD8 T-suppressor cells secreting IL-10.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity：Recognizes mouse RPSA. Species Crossreactivity: bovine, canine, goat, equine, human, porcine, rabbit, rat, sheep, zebrafish
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Bo Ca Eq Gt Hu Mo Po Rb Rt Sh Ze
Immunogen：Synthetic peptide corresponding to a region of mouse RPSA.
