84-5050-83　RNPC3 (RNA-Binding Protein 40, RNA-Binding Region (RNP1, RRM) Containing 3) 100ul　490736

特徴

• RNPC3 is an RNA-binding protein involved in pre-mRNA splicing.
• RNPC3 participates in pre-mRNA U12-dependent splicing.
• RNPC3 binds to the 3'-stem-loop of m7G-capped U12 snRNA.Two types of spliceosomes catalyze splicing of pre-mRNAs.
• The major U2-type spliceosome is found in all eukaryotes and removes U2-type introns, which represent more than 99% of pre-mRNA introns.
• The minor U12-type spliceosome is found in some eukaryotes and removes U12-type introns, which are rare and have distinct splice consensus signals.
• The U12-type spliceosome consists of several small nuclear RNAs and associated proteins.
• This gene encodes a 65K protein that is a component of the U12-type spliceosome.
• This protein contains two RNA recognition motifs (RRMs), suggesting that it may contact one of the small nuclear RNAs of the minor spliceosome.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.