84-5046-03　RBMXL2 (RNA-Binding Motif Protein, X-lLnked-Like-2) 100ul　490259

特徴

• The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA).
• These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport.
• While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm.
• The hnRNP proteins have distinct nucleic acid binding properties.
• RBMXL2 has two RRM domains that bind RNAs.
• RBMXL2 has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator.
• It primarily localizes to the nuclei of meiotic spermatocytes.
• This gene is a candidate for autosomal male infertility.This gene belongs to the HNRPG subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs).
• The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA).
• These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport.
• While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm.
• The hnRNP proteins have distinct nucleic acid binding properties.
• The protein encoded by this gene has two RRM domains that bind RNAs.
• This gene is intronless and is thought to be derived from a processed retroposon.
• However, unlike many retroposon-derived genes, this gene is not a pseudogene.
• The encoded protein has similarity to HNRPG and RBMY proteins and it is suggested to replace HNRPG protein function during meiotic prophase or act as a germ cell-specific splicing regulator.
• It primarily localizes to the nuclei of meiotic spermatocytes.
• This gene is a candidate for autosomal male infertility.
• Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly.
• The genomic coordinates used for the transcript record were based on alignments.
• PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-2215 AC100875.3 67063-69277 c
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.