84-5045-16　RBBP8 (Retinoblastoma Binding Protein 8, DNA endonuclease RBBP8 Ensembl ENSP00000382630) 100ul　490173

特徴

• RBBP8 is a ubiquitously expressed nuclear protein.
• It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation.
• This protein complexes with transcriptional co-repressor CTBP.
• It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control.
• It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1.
• Three transcript variants encoding two different isoforms have been found for this gene.
• More transcript variants exist, but their full-length natures have not been determined.The protein encoded by this gene is a ubiquitously expressed nuclear protein.
• It is found among several proteins that bind directly to retinoblastoma protein, which regulates cell proliferation.
• This protein complexes with transcriptional co-repressor CTBP.
• It is also associated with BRCA1 and is thought to modulate the functions of BRCA1 in transcriptional regulation, DNA repair, and/or cell cycle checkpoint control.
• It is suggested that this gene may itself be a tumor suppressor acting in the same pathway as BRCA1.
• Three transcript variants encoding two different isoforms have been found for this gene.
• More transcript variants exist, but their full-length natures have not been determined.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.