84-5044-32　RARB (Retinoic Acid Receptor Beta) 100ul　490090

特徴

• RARB is a retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators.
• This receptor localizes to the cytoplasm and to subnuclear compartments.
• It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation.
• It is thought that this protein limits growth of many cell types by regulating gene expression.
• This gene encodes retinoic acid receptor beta, a member of the thyroid-steroid hormone receptor superfamily of nuclear transcriptional regulators.
• This receptor localizes to the cytoplasm and to subnuclear compartments.
• It binds retinoic acid, the biologically active form of vitamin A which mediates cellular signalling in embryonic morphogenesis, cell growth and differentiation.
• It is thought that this protein limits growth of many cell types by regulating gene expression.
• The gene was first identified in a hepatocellular carcinoma where it flanks a hepatitis B virus integration site.
• The gene expresses at least two transcript variants; one additional transcript has been described, but its full length nature has not been determined.
• Applications:Suitable for use in Immunohistochemistry, Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.