RAPGEF1 is a human guanine nucleotide exchange factor.
It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases.
This signaling cascade protein may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation.This gene encodes a human guanine nucleotide exchange factor.
It transduces signals from CRK by binding the SH3 domain of CRK, and activating several members of the Ras family of GTPases.
This signaling cascade that may be involved in apoptosis, integrin-mediated signal transduction, and cell transformation.
Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some variants has not been determined.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity：Recognizes human RAPGEF1.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to the C-terminal region of human RAPGEF1
