84-5041-18　PUF60 (Poly(U)-Binding-Splicing Factor PUF60, Poly-U Binding Splicing Factor 60KD) 100ul　489779

特徴

• PUF60 is a Ro RNP-binding protein.
• It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs.
• This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein.
• It can repress a c-myc reporter via the FUSE.
• It is also known to target transcription factor IIH and inhibit activated transcription.The protein encoded by this gene is a Ro RNP-binding protein.
• It interacts with Ro RNPs and their interaction is thought to represent a gain of function for Ro RNPs.
• This protein also forms a ternary complex with far upstream element (FUSE) and FUSE-binding protein.
• It can repress a c-myc reporter via the FUSE.
• It is also known to target transcription factor IIH and inhibit activated transcription.
• This gene is implicated in the xeroderma pigmentosum disorder.
• There are two alternatively spliced transcript variants of this gene encoding different isoforms.
• There seems to be evidence of multiple polyadenylation sites for this gene.
• Applications:Suitable for use in Immunohistochemistry, Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.