84-5039-46　PSMC3IP (Homologous-Pairing Protein 2 Homolog, PSMC3 Interacting Protein) 100ul　489609

特徴

• PSMC3IP plays an important role in meiotic recombination.
• It stimulates DMC1-mediated strand exchange required for pairing homologous chromosomes during meiosis.
• The complex PSMC3IP/MND1 binds DNA, stimulates the recombinase activity of DMC1 as well as DMC1 D-loop formation from double-strand DNA.
• This complex stabilizes presynaptic RAD51 and DMC1 filaments formed on single strand DNA to capture double-strand DNA.
• This complex stimulates both synaptic and presynaptic critical steps in RAD51 and DMC1-promoted homologous pairing.
• It may inhibit HIV-1 viral protein TAT activity and modulate the activity of proteasomes through association with PSMC3.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.