PPP1R13B is a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins.
The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions.
ASPP proteins are required for the induction of apoptosis by p53-family proteins.
They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes.
Expression of this gene is regulated by the E2F transcription factor.This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins.
The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions.
ASPP proteins are required for the induction of apoptosis by p53-family proteins.
They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes.
Expression of this gene is regulated by the E2F transcription factor.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size:100ul
Host:rabbit
Source Antibody:human
Grade:Affinity Purified
Purity:Purified by affinity chromatography.
Form:Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity:Recognizes human PPP1R13B.
Isotype:IgG
Calc Applications Abbrev:WB
Calc Crossreactivity:Hu
Immunogen:Synthetic peptide corresponding to the middle region of human PPP1R13B