84-5027-37 PELI2 (E3 Ubiquitin-Protein Ligase Pellino Homolog 2, Pellino E3 Ubiquitin Protein Ligase Family Member 2) 100ul 488411
特徴
- PELI2 is a E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins.
- It is involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6.
- It mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination.
- It may be important for LPS- and IL1B-induced MAP3K7- dependent, but not MAP3K3-dependent, NF-kappa-B activation.
- And it can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1.
- Applications:Suitable for use in Western Blot.
- Other applications not tested.
- Recommended Dilution:Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by affinity chromatography.
- Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
- Specificity：Recognizes human PELI2.
- Isotype：IgG
- Calc Applications Abbrev：WB
- Calc Crossreactivity：Hu
- Immunogen：Synthetic peptide corresponding to the N-terminal region of Human PELI2
- Shelf Life：1year
- Swiss Prot Number：Q9HAT8
- EU Commodity Code：30021010
- この商品は法規制を確認しておりません。（法規制によって販売できない場合もございます）
- 製品の仕様は予告なく変更になる場合がございます。最新仕様はメーカーホームページをご確認ください。
- 【試薬に関するお問合せ】
- アズワン株式会社 試薬・プロセス材料グループ
- TEL：06-6447-8641
- FAX：06-6447-8642
- E-mail：[email protected]
