Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis.
Potent mitogen and chemoattractant for cells of mesenchymal origin.
Required for normal skeleton formation during embryonic development, especially for normal development of the craniofacial skeleton and for normal development of the palate.
Required for normal skin morphogenesis during embryonic development.
Plays an important role in wound healing, where it appears to be involved in three stages: inflammation, proliferation and remodeling.
Plays an important role in angiogenesis and blood vessel development.
Involved in fibrotic processes, in which transformation of interstitial fibroblasts into myofibroblasts plus collagen deposition occurs.
The CUB domain has mitogenic activity in coronary artery smooth muscle cells, suggesting a role beyond the maintenance of the latency of the PDGF domain.
In the nucleus, PDGFC seems to have additional function.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity：Recognizes PDGFC. Species Crossreactivity: equine, human, mouse, rabbit, rat
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Eq Hu Mo Rb Rt
Immunogen：Synthetic peptide corresponding to the N-terminal region of Mouse Pdgfc
