This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily.
PCDH8 is an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner.
Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons.
Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region.This gene belongs to the protocadherin gene family, a subfamily of the cadherin superfamily.
The gene encodes an integral membrane protein that is thought to function in cell adhesion in a CNS-specific manner.
Unlike classical cadherins, which are generally encoded by 15-17 exons, this gene includes only 3 exons.
Notable is the large first exon encoding the extracellular region, including 6 cadherin domains and a transmembrane region.
Alternative splicing yields isoforms with unique cytoplasmic tails.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity：Recognizes human PCDH8.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to the middle region of human PCDH8
