84-5016-29　NTAN1 (Protein N-terminal Asparagine Amidohydrolase, N-terminal Asparagine Amidase) 100ul　487314

特徴

• The protein encoded by this gene functions in a step-wise process of protein degradation through the N-end rule pathway.
• This protein acts as a tertiary destabilizing enzyme that deamidates N-terminal L-Asn residues on proteins to produce N-terminal L-Asp.
• L-Asp substrates are subsequently conjugated to L-Arg, which is recognized by specific E3 ubiquitin ligases and targeted to the proteasome.
• Pseudogenes of this gene are located on the long arms of chromosomes 8, 10 and 12.
• Alternative splicing results in multiple transcript variants that encode different protein isoforms.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.