84-5015-96 NSMCE2 (E3 SUMO-Protein Ligase NSE2, Non-SMC Element 2, MMS21 Homolog (S. Cerevisiae)) 100ul 487282
特徴
- NSMCE2 is the E3 SUMO-protein ligase component of the SMC5-SMC6 complex, a complex involved in DNA double-strand breaks by homologous recombination.
- The complex may promote sister chromatid homologous recombination by recruiting the SMC1-SMC3 cohesin complex to double-strand breaks.
- NSMCE2 acts as a E3 ligase mediating SUMO attachment to various proteins such as SMC6L1 and TRAX, and maybe the cohesin components RAD21 and STAG2.
- SUMO protein-ligase activity is required for the prevention of DNA damage-induced apoptosis by facilitating DNA repair.
- Applications:Suitable for use in Western Blot.
- Other applications not tested.
- Recommended Dilution:Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by affinity chromatography.
- Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
- Specificity：Recognizes human NSMCE2.
- Isotype：IgG
- Calc Applications Abbrev：WB
- Calc Crossreactivity：Hu
- Immunogen：Synthetic peptide corresponding to the middle region of human NSMCE2
- Shelf Life：1year
- Swiss Prot Number：Q96MF7
- EU Commodity Code：30021010
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