84-5015-60　NRCAM (Neuronal Cell Adhesion Molecule) 100ul　487246

特徴

• Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily.
• NRCAM is a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains.
• This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth.
• NRCAM may also play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration.
• Allelic variants of its gene have been associated with autism and addiction vulnerability.Cell adhesion molecules (CAMs) are members of the immunoglobulin superfamily.
• This gene encodes a neuronal cell adhesion molecule with multiple immunoglobulin-like C2-type domains and fibronectin type-III domains.
• This ankyrin-binding protein is involved in neuron-neuron adhesion and promotes directional signaling during axonal cone growth.
• This gene is also expressed in non-neural tissues and may play a general role in cell-cell communication via signaling from its intracellular domain to the actin cytoskeleton during directional cell migration.
• Allelic variants of this gene have been associated with autism and addiction vulnerability.
• Alternative splicing results in multiple transcript variants encoding different isoforms.
• Applications:Suitable for use in Immunohistochemistry, Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.