84-5015-55　NRBF2 (Nuclear Receptor-Binding Factor 2) 100ul　487241

特徴

• May modulate transcriptional activation by target nuclear receptors.
• Can act as transcriptional activator (in vitro).Involved in starvation-induced autophagy probably by its association with PI3K complex I (PI3KC3-C1).
• However, effects has been described variably.
• Involved in the induction of starvation-induced autophagy.
• Stabilzes PI3KC3-C1 assembly and enhances ATG14-linked lipid kinase activity of PIK3C3.
• Proposed to negatively regulate basal and starvation-induced autophagy and to inhibit PIK3C3 activity by modulating interactions in PI3KC3-C1.
• May be involved in autophagosome biogenesis.
• May play a role in neural progenitor cell survival during differentiation.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.