Nkx2-2 contains 1 homeobox DNA-binding domain which is essential for interaction with OLIG2.
Nkx2-2 may be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance.
This gene encodes a member of the NK family of homeobox-containing proteins.
The encoded protein may play a role in skeletal development.
Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript was available for the full length of the gene.
The extent of this transcript is supported by transcript alignments.