84-5010-14　NDUFS2 (NADH Dehydrogenase [Ubiquinone] Iron-Sulfur Protein 2, Mitochondrial, NADH:Ubiquinone Oxidoreductase Core Subunit S2) 100ul　486705

特徴

• The protein encoded by this gene is a core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I).
• Mammalian mitochondrial complex I is composed of at least 43 different subunits, 7 of which are encoded by the mitochondrial genome, and the rest are the products of nuclear genes.
• The iron-sulfur protein fraction of complex I is made up of 7 subunits, including this gene product.
• Complex I catalyzes the NADH oxidation with concomitant ubiquinone reduction and proton ejection out of the mitochondria.
• Mutations in this gene are associated with mitochondrial complex I deficiency.
• Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.