84-5006-06　MTRR (5-Methyltetrahydrofolate-Homocysteine Methyltransferase Reductase, Methionine Synthase Reductase) 100ul　486301

特徴

• Methionine is an essential amino acid required for protein synthesis and one-carbon metabolism.
• Its synthesis is catalyzed by the enzyme methionine synthase.
• Methionine synthase eventually becomes inactive due to the oxidation of its cob(I)alamin cofactor.
• The protein encoded by this gene regenerates a functional methionine synthase via reductive methylation.
• It is a member of the ferredoxin-NADP(+) reductase (FNR) family of electron transferases.
• Patients of the cbl-E complementation group of disorders of folate/cobalamin metabolism are defective in reductive activation of methionine synthase.
• Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.