84-4999-52　MED27 (Mediator of RNA Polymerase II Transcription Subunit 27, Mediator Complex Subunit 27) 100ul　485654

特徴

• The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA.
• These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus.
• CRSP8 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1.
• CRSP8 is also a component of other multisubunit complexes e.g.
• thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA.
• These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus.
• The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1.
• This protein is also a component of other multisubunit complexes e.g.
• thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.