MAP3K2 is a component of a protein kinase signal transduction cascade.
It regulates the JNK and ERK5 pathways by phosphorylating and activating MAP2K5 and MAP2K7.
It also plays a role in caveolae kiss-and-run dynamics.The protein encoded by this gene is a member of serine/threonine protein kinase family.
This kinase preferentially activates other kinases involved in the MAP kinase signaling pathway.
This kinase has been shown to directly phosphorylate and activate Ikappa B kinases, and thus plays a role in NF-kappa B signaling pathway.
This kinase has also been found to bind and activate protein kinase C-related kinase 2, which suggests its involvement in a regulated signaling process.