84-4991-47　LMBR1 (Limb Region 1 Protein Homolog, Limb Region 1 Homolog (Mouse)) 100ul　484854

特徴

• LMBR1 is a member of the LMBR1-like membrane protein family.
• Another member of this protein family has been shown to be a lipocalin transmembrane receptor.
• A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of LMBR1 gene.
• Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if LMBR1 gene functions directly in limb development.
• Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression.This gene encodes a member of the LMBR1-like membrane protein family.
• Another member of this protein family has been shown to be a lipocalin transmembrane receptor.
• A highly conserved, cis-acting regulatory module for the sonic hedgehog gene is located within an intron of this gene.
• Consequently, disruption of this genic region can alter sonic hedgehog expression and affect limb patterning, but it is not known if this gene functions directly in limb development.
• Mutations and chromosomal deletions and rearrangements in this genic region are associated with acheiropody and preaxial polydactyly, which likely result from altered sonic hedgehog expression.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.