84-4988-49　KTN1 (Kinectin, Kinectin 1 (Kinesin Receptor)) 100ul　484559

特徴

• Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm.
• Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment of lysosomes along microtubules are all related processes.
• The transport of organelles requires a special class of microtubule-associated proteins (MAPs).
• One of these is the molecular motor kinesin, an ATPase that moves vesicles unidirectionally toward the plus end of the microtubule.
• Another such MAP is kinectin, a large integral ER membrane protein.
• Antibodies directed against kinectin have been shown to inhibit its binding to kinesin.Various cellular organelles and vesicles are transported along the microtubules in the cytoplasm.
• Likewise, membrane recycling of the endoplasmic reticulum (ER), Golgi assembly at the microtubule organizing center, and alignment of lysosomes along microtubules are all related processes.
• The transport of organelles requires a special class of microtubule-associated proteins (MAPs).
• One of these is the molecular motor kinesin (see MIM 148760 and MIM 600025), an ATPase that moves vesicles unidirectionally toward the plus end of the microtubule.
• Another such MAP is kinectin, a large integral ER membrane protein.
• Antibodies directed against kinectin have been shown to inhibit its binding to kinesin.[supplied by OMIM].
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.