KIF2A belongs to the kinesin-like protein family, MCAK/KIF2 subfamily.
It contains 1 kinesin-motor domain.
KIF2A plus end-directed microtubule-dependent motor required for normal brain development.
It may regulate microtubule dynamics during axonal growth.
KIF2A is implicated in formation of bipolar mitotic spindles.
It has microtubule depolymerization activity.
Hela cells lacking KIF2A show asymmetric or monopolar mitotic spindles.
Osteosarcoma cells (U2OS) lacking KIF2A or KIF2B show disorganised or monopolar mitotic spindles.Kinesins, such as KIF2, are microtubule-associated motor proteins.
For background information on kinesins, see MIM 148760.[supplied by OMIM].
Applications:Suitable for use in Immunohistochemistry, Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity：Recognizes human KIF2A.
Isotype：IgG
Calc Applications Abbrev：IHC WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to the N-terminal region of human KIF2A
