84-4980-42　ITGAV (Integrin Alpha-V, Integrin Subunit Alpha V) 100ul　483760

特徴

• The product of this gene belongs to the integrin alpha chain family.
• Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling.
• The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha V subunit.
• This subunit associates with beta 1, beta 3, beta 5, beta 6 and beta 8 subunits.
• The heterodimer consisting of alpha V and beta 3 subunits is also known as the vitronectin receptor.
• This integrin may regulate angiogenesis and cancer progression.
• Alternative splicing results in multiple transcript variants.
• Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.