84-4979-92　ISCU (iron-Sulfur Cluster Assembly Enzyme ISCU, Mitochondrial, Iron-Sulfur Cluster Assembly Enzyme) 100ul　483711

特徴

• Iron-sulfur (Fe-S) clusters are necessary for several mitochondrial enzymes and other subcellular compartment proteins.
• They contain sulfur and iron, and are created via several steps that include cysteine desulfurases, iron donors, chaperones, and scaffold proteins.
• This gene encodes the two isomeric forms, ISCU1 and ISCU2, of the Fe-S cluster scaffold protein.
• Mutations in this gene have been found in patients with myopathy with severe exercise intolerance and myoglobinuria.
• A pseudogene of this gene is present on chromosome 1.
• Alternative splicing results in multiple transcript variants encoding different isoforms.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.