84-4977-87　IL4 (Interleukin-4) 100ul　483508

特徴

• IL4 is a pleiotropic cytokine produced by activated T cells.
• This cytokine is a ligand for interleukin 4 receptor.
• The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13.
• STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine.
• The protein encoded by this gene is a pleiotropic cytokine produced by activated T cells.
• This cytokine is a ligand for interleukin 4 receptor.
• The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13.
• STAT6, a signal transducer and activator of transcription, has been shown to play a central role in mediating the immune regulatory signal of this cytokine.
• This gene, IL3, IL5, IL13, and CSF2 form a cytokine gene cluster on chromosome 5q, with this gene particularly close to IL13.
• This gene, IL13 and IL5 are found to be regulated coordinately by several long-range regulatory elements in an over 120 kilobase range on the chromosome.
• Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.