84-4977-16　IKZF3 (Zinc Finger Protein Aiolos, IKAROS Family Zinc Finger 3 (Aiolos)) 100ul　483437

特徴

• IKZF3 is a member of the Ikaros family of zinc-finger proteins.
• Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoetic-specific transcription factors involved in the regulation of lymphocyte development.
• This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation.
• Both Ikaros and Aiolos can participate in chromatin remodeling.
• Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers.
• At least six alternative transcripts encoding different isoforms have been described.This gene encodes a member of the Ikaros family of zinc-finger proteins.
• Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development.
• This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation.
• Both Ikaros and Aiolos can participate in chromatin remodeling.
• Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers.
• At least six alternative transcripts encoding different isoforms have been described.
• Applications:Suitable for use in Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.