84-4975-19　HYAL1 (Hyaluronidase-1, Hyaluronoglucosaminidase 1) 100ul　483242

特徴

• HYAL1 is a lysosomal hyaluronidase.
• Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix.
• Hyaluronan is thought to be involved in cell proliferation, migration and differentiation.
• This enzyme is active at an acidic pH and is the major hyaluronidase in plasma.
• Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.
• This gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression.
• Multiple transcript variants encoding different isoforms have been found for this gene.This gene encodes a lysosomal hyaluronidase.
• Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix.
• Hyaluronan is thought to be involved in cell proliferation, migration and differentiation.
• This enzyme is active at an acidic pH and is the major hyaluronidase in plasma.
• Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.
• The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression.
• Multiple transcript variants encoding different isoforms have been found for this gene.
• Applications:Suitable for use in Western Blot, Immunohistochemistry.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.