HMGA2 belongs to the non-histone chromosomal high mobility group (HMG) protein family.
HMG proteins function as architectural factors and are essential components of the enhancesome.
This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor.
It may be play a role in adipogenesis, mesenchymal differentiation and diet-induced obesity.This gene encodes a protein that belongs to the non-histone chromosomal high mobility group (HMG) protein family.
HMG proteins function as architectural factors and are essential components of the enhancesome.
This protein contains structural DNA-binding domains and may act as a transcriptional regulating factor.
Identification of the deletion, amplification, and rearrangement of this gene that are associated with myxoid liposarcoma suggests a role in adipogenesis and mesenchymal differentiation.
A gene knock out study of the mouse counterpart demonstrated that this gene is involved in diet-induced obesity.
Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Applications:Suitable for use in Western Blot.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：human
Grade：Affinity Purified
Purity：Purified by Protein A affinity chromatography.
Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity：Recognizes human HMGA2.
Isotype：IgG
Calc Applications Abbrev：WB
Calc Crossreactivity：Hu
Immunogen：Synthetic peptide corresponding to the N-terminal region of human HMGA2
