84-4968-76　HDAC9 (Histone Deacetylase 9) 100ul　482606

特徴

• Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events.
• Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.
• HDAC9 has sequence homology to members of the histone deacetylase family.
• The MITR protein lacks the histone deacetylase catalytic domain.
• It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs.
• HDAC9 may play a role in hematopoiesis.Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events.
• Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.
• The protein encoded by this gene has sequence homology to members of the histone deacetylase family.
• This gene is orthologous to the Xenopus and mouse MITR genes.
• The MITR protein lacks the histone deacetylase catalytic domain.
• It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs.
• This encoded protein may play a role in hematopoiesis.
• Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.
• Applications:Suitable for use in CHIP, Immunohistochemistry, Western Blot.
• Other applications not tested.
• Recommended Dilution:Optimal dilutions to be determined by the researcher.
• Storage and Stability:May be stored at 4°C for short-term only.
• Aliquot to avoid repeated freezing and thawing.
• Store at -20°C.
• Aliquots are stable for 12 months after receipt.
• For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.