Hdac6 is responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4).
Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events.
Histone deacetylases act via the formation of large multiprotein complexes.
Hdac6 plays a central role in microtubule-dependent cell motility via deacetylation of tubulin.
Applications:Suitable for use in Western Blot, CHIP, Immunohistochemistry.
Other applications not tested.
Recommended Dilution:Optimal dilutions to be determined by the researcher.
Storage and Stability:May be stored at 4°C for short-term only.
Aliquot to avoid repeated freezing and thawing.
Store at -20°C.
Aliquots are stable for 12 months after receipt.
For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
Size：100ul
Host：rabbit
Source Antibody：mouse
Grade：Affinity Purified
Purity：Purified by affinity chromatography.
Form：Supplied as a liquid in PBS, 2% sucrose, 0.09% sodium azide.
Specificity：Recognizes HDAC6. Species Crossreactivity: bovine, canine, guinea pig, equine, human, mouse, porcine, rabbit, rat
Isotype：IgG
Calc Applications Abbrev：ChIP IHC WB
Calc Crossreactivity：Bo Ca Eq Gp Hu Mo Po Rb Rt
Immunogen：Synthetic peptide corresponding to the C-terminal region of Mouse Hdac6
