84-4968-68 HDAC4 (Histone Deacetylase 4) 100ul 482598
特徴
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events.
- Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA.
- The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family.
- It possesses histone deacetylase activity and represses transcription when tethered to a promoter.
- This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D.
- It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
- Applications:Suitable for use in Western Blot.
- Other applications not tested.
- Recommended Dilution:Optimal dilutions to be determined by the researcher.
- Storage and Stability:May be stored at 4°C for short-term only.
- Aliquot to avoid repeated freezing and thawing.
- Store at -20°C.
- Aliquots are stable for 12 months after receipt.
- For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
仕様
- Size：100ul
- Host：rabbit
- Source Antibody：human
- Grade：Affinity Purified
- Purity：Purified by affinity chromatography.
- Form：Supplied as a liquid in PBS, 29% sucrose, 0.09% sodium azide.
- Specificity：Recognizes human HDAC4.
- Isotype：IgG
- Calc Applications Abbrev：WB
- Calc Crossreactivity：Hu
- Immunogen：Synthetic peptide corresponding to the N-terminal region of human HDAC4
- Shelf Life：1year
- Swiss Prot Number：P56524
- EU Commodity Code：30021010
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